Pain and the endogenous antinociceptive neuronal system: physiologic role of oxytocin

Authors

  • Marcelo Moraes Valença Universidade Federal de Pernambuco
  • Luciana Patrízia A. Andrade-Valença Universidade Federal de Pernambuco
  • José Antunes-Rodrigues Universidade de São Paulo

DOI:

https://doi.org/10.48208/HeadacheMed.2011.26

Keywords:

Pain, Headache, Oxytocin, Carpal tunnel syndrome

Abstract

The unpleasant pain sensation is a sub-modality of somatic sensation that exerts fundamental warning and protective functions. Pain is the more frequent complain in a neurological outpatient clinic. In a series of 200 consecutive patients in a neurological outpatient clinic, 51% of them complained of some type of pain, the more frequents were headache and carpal tunnel syndrome. The role of oxytocin in pain regulation was reviewed. It seems that oxytocin may play a major role in the mechanism of pain regulation, particularly through the endogenous antinociceptive neuronal system.

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Author Biographies

Marcelo Moraes Valença, Universidade Federal de Pernambuco

Neurology and Neurosurgery Unit, Department of Neuropsychiatry, CCS, Universidade Federal de Pernambuco, Recife, PE, Brazil

Luciana Patrízia A. Andrade-Valença, Universidade Federal de Pernambuco

Neurology and Neurosurgery Unit, Department of Neuropsychiatry, CCS, Universidade Federal de Pernambuco, Recife, PE, Brazil
Division of Neurology, Universidade de Pernambuco, Recife, Brazil

José Antunes-Rodrigues, Universidade de São Paulo

Department of Physiology, School of Medicine of Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil

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Published

2011-12-31

How to Cite

1.
Valença MM, Andrade-Valença LPA, Antunes-Rodrigues J. Pain and the endogenous antinociceptive neuronal system: physiologic role of oxytocin. Headache Med [Internet]. 2011 Dec. 31 [cited 2024 Dec. 13];2(4):182-6. Available from: https://headachemedicine.com.br/index.php/hm/article/view/188

Issue

Section

Review

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