Relato de caso: Olhe nos meus olhos
DOI:
https://doi.org/10.48208/HeadacheMed.2022.38Palavras-chave:
Enxaqueca, Transtornos de neurodesenvolvimento, Transtorno do espectro autista, Crianças, AdolescentesResumo
A comorbidade entre migrânea e o Transtorno do Espectro Autista (TEA) ainda não é bem estabelecida. Apesar de evidências plausíveis dessa comorbidade, são escassos os estudos populacionais que explorem essa hipótese. O diagnóstico de migrânea em crianças com TEA é muito desafiador devido à grande heterogeneidade clínica e limitadas habilidades de comunicação observadas no TEA, particularmente as habilidades verbais em crianças pequenas e com deficiência intelectual associada. O TEA e a migrânea são condições crônicas prevalentes que apresentam algumas alterações fisiopatológicas comuns (desregulação da neurotransmissão, resposta imune alterada, achados anormais na organização de minicolunas corticais e disfunções no eixo intestino-cérebro), genes de suscetibilidade (incluindo mutações e polimorfismos de canais de cálcio) e processamento sensorial atípico. Aqui, aproveitamos um caso prototípico de um adolescente com migrânea episódica transformada em crônica, não responsiva ao tratamento preventivo, para explorar a investigação diagnóstica e um manejo clínico e terapêutico personalizado bem-sucedido.
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Copyright (c) 2022 Marco Antonio Arruda, Renato Arruda
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
