The importance of addressing sleep disorders in migraine treatment

Authors

DOI:

https://doi.org/10.48208/HeadacheMed.2022.20

Keywords:

Migraine, Sleep disorders, Treatment, Triggers, Prodromal symptoms

Abstract

Abstract

Migraine is one of the most common complaints in the clinical practice of neurology. It is multifactorial, with insomnia being a predisposing factor present in almost 50% of cases. The pathophysiology of migraine is complex and involves changes in several areas of the CNS, which find common pathways with sleep disorders. Among them, hypothalamic connections, hormones and neuropeptides such as orexias and monoaminergics. Furthermore, other specific sleep disorders are related to migraine. Currently, treatment is individualized and in addition to medication measures, changes in lifestyle and sleep adjustments are proposed. In view of this, the association between sleep and migraine is a therapeutic opportunity and this can be done based on a detailed clinical approach during the consultation.

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References

Kelman L. The triggers or precipitants of the acute migraine attack. Cephalalgia 2007;27(5):394-402 Doi:10.1111/j.1468-2982.2007.01303.x DOI: https://doi.org/10.1111/j.1468-2982.2007.01303.x

Kim J, Cho SJ, Kim WJ, Yang KI, Yun CH and Chu MK. Impact of migraine on the clinical presentation of insomnia: a population-based study. J Headache Pain 2018;19(1):86 Doi:10.1186/s10194-018-0916-5 DOI: https://doi.org/10.1186/s10194-018-0916-5

Dodick DW, Eross EJ, Parish JM and Silber M. Clinical, anatomical, and physiologic relationship between sleep and headache. Headache 2003;43(3):282-292 Doi:10.1046/j.1526-4610.2003.03055.x DOI: https://doi.org/10.1046/j.1526-4610.2003.03055.x

Dexter JD and Weitzman ED. The relationship of nocturnal headaches to sleep stage patterns. Neurology 1970;20(5):513-518 Doi:10.1212/wnl.20.5.513 DOI: https://doi.org/10.1212/WNL.20.5.513

Wöber C, Brannath W, Schmidt K, Kapitan M, Rudel E, Wessely P and Wöber-Bingöl C. Prospective analysis of factors related to migraine attacks: the PAMINA study. Cephalalgia 2007;27(4):304-314 Doi:10.1111/j.1468-2982.2007.01279.x DOI: https://doi.org/10.1111/j.1468-2982.2007.01279.x

Alstadhaug K, Salvesen R and Bekkelund S. Insomnia and circadian variation of attacks in episodic migraine. Headache 2007;47(8):1184-1188 Doi:10.1111/j.1526-4610.2007.00858.x DOI: https://doi.org/10.1111/j.1526-4610.2007.00858.x

Drake ME, Jr., Pakalnis A, Andrews JM and Bogner JE. Nocturnal sleep recording with cassette EEG in chronic headaches. Headache 1990;30(9):600-603 Doi:10.1111/j.1526-4610.1990.hed3009600.x DOI: https://doi.org/10.1111/j.1526-4610.1990.hed3009600.x

Othmer E, Hayden MP and Segelbaum R. Encephalic cycles during sleep and wakefulness in humans: a 24-hour pattern. Science 1969;164(3878):447-449 Doi:10.1126/science.164.3878.447 DOI: https://doi.org/10.1126/science.164.3878.447

Pavlova MK and Latreille V. Sleep Disorders. Am J Med 2019;132(3):292-299 Doi:10.1016/j.amjmed.2018.09.021 DOI: https://doi.org/10.1016/j.amjmed.2018.09.021

Ashina M, Katsarava Z, Do TP, Buse DC, Pozo-Rosich P, Özge A, . . . Lipton RB. Migraine: epidemiology and systems of care. Lancet 2021;397(10283):1485-1495 Doi:10.1016/s0140-6736(20)32160-7 DOI: https://doi.org/10.1016/S0140-6736(20)32160-7

Lipton RB, Bigal ME, Diamond M, Freitag F, Reed ML and Stewart WF. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology 2007;68(5):343-349 Doi:10.1212/01.wnl.0000252808.97649.21 DOI: https://doi.org/10.1212/01.wnl.0000252808.97649.21

Global, regional, and national burden of migraine and tension-type headache, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol 2018;17(11):954-976 Doi:10.1016/s1474-4422(18)30322-3 DOI: https://doi.org/10.1016/S1474-4422(18)30322-3

Auer M, Frauscher B, Hochleitner M and Högl B. Gender-Specific Differences in Access to Polysomnography and Prevalence of Sleep Disorders. J Womens Health (Larchmt) 2018;27(4):525-530 Doi:10.1089/jwh.2017.6482 DOI: https://doi.org/10.1089/jwh.2017.6482

Zhang B and Wing YK. Sex differences in insomnia: a meta-analysis. Sleep 2006;29(1):85-93

Doi:10.1093/sleep/29.1.85 DOI: https://doi.org/10.1093/sleep/29.1.85

Pengo MF, Won CH and Bourjeily G. Sleep in Women Across the Life Span. Chest 2018;154(1):196-206 Doi:10.1016/j.chest.2018.04.005 DOI: https://doi.org/10.1016/j.chest.2018.04.005

Caufriez A, Leproult R, L'Hermite-Balériaux M, Kerkhofs M and Copinschi G. Progesterone

prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women. J Clin Endocrinol Metab 2011;96(4):E614-623 Doi:10.1210/jc.2010-2558 DOI: https://doi.org/10.1210/jc.2010-2558

Mong JA, Baker FC, Mahoney MM, Paul KN, Schwartz MD, Semba K and Silver R. Sleep, rhythms, and the endocrine brain: influence of sex and gonadal hormones. J Neurosci 2011;31(45):16107-16116 Doi:10.1523/jneurosci.4175-11.2011 DOI: https://doi.org/10.1523/JNEUROSCI.4175-11.2011

Luckhaupt SE, Tak S and Calvert GM. The prevalence of short sleep duration by industry and occupation in the National Health Interview Survey. Sleep 2010;33(2):149-159 Doi:10.1093/sleep/33.2.149 DOI: https://doi.org/10.1093/sleep/33.2.149

Knutson KL, Van Cauter E, Rathouz PJ, DeLeire T and Lauderdale DS. Trends in the prevalence of short sleepers in the USA: 1975-2006. Sleep 2010;33(1):37-45 Doi:10.1093/sleep/33.1.37 DOI: https://doi.org/10.1093/sleep/33.1.37

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia 2018;38(1):1-211 Doi:10.1177/0333102417738202 DOI: https://doi.org/10.1177/0333102417738202

Sateia MJ. International classification of sleep disorders-third edition: highlights and modifications. Chest 2014;146(5):1387-1394 Doi:10.1378/chest.14-0970 DOI: https://doi.org/10.1378/chest.14-0970

Cutrer FM B, ZH, Sabahat A. Pathophysiology, clinical manifestations, and diagnosis of migraine in adults. Up to Date 2012;

Judd BG SM. Classification of sleep disorders. Up to Date 2021;

Martin VT and Behbehani MM. Toward a rational understanding of migraine trigger factors. Med Clin North Am 2001;85(4):911-941 Doi:10.1016/s0025-7125(05)70351-5 DOI: https://doi.org/10.1016/S0025-7125(05)70351-5

Lipton RB, Serrano D, Nicholson RA, Buse DC, Runken MC and Reed ML. Impact of NSAID and Triptan use on developing chronic migraine: results from the American Migraine Prevalence and Prevention (AMPP) study. Headache 2013;53(10):1548-1563 Doi:10.1111/head.12201 DOI: https://doi.org/10.1111/head.12201

Giffin NJ, Ruggiero L, Lipton RB, Silberstein SD, Tvedskov JF, Olesen J, . . . Macrae A. Premonitory symptoms in migraine: an electronic diary study. Neurology 2003;60(6):935-940 Doi:10.1212/01.wnl.0000052998.58526.a9 DOI: https://doi.org/10.1212/01.WNL.0000052998.58526.A9

Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurol 2018;17(2):174-182 Doi:10.1016/s1474-4422(17)30435-0 DOI: https://doi.org/10.1016/S1474-4422(17)30435-0

Schulte LH, Jürgens TP and May A. Photo-, osmo- and phonophobia in the premonitory phase of migraine: mistaking symptoms for triggers? J Headache Pain 2015;16(14 Doi:10.1186/s10194-015-0495-7 DOI: https://doi.org/10.1186/s10194-015-0495-7

Maniyar FH, Sprenger T, Schankin C and Goadsby PJ. The origin of nausea in migraine-a PET study. J Headache Pain 2014;15(1):84 Doi:10.1186/1129-2377-15-84 DOI: https://doi.org/10.1186/1129-2377-15-84

Wang T, Chen N, Zhan W, Liu J, Zhang J, Liu Q, . . . Gong Q. Altered effective connectivity of posterior thalamus in migraine with cutaneous allodynia: a resting-state fMRI study with Granger causality analysis. J Headache Pain 2015;17(17 Doi:10.1186/s10194-016-0610-4 DOI: https://doi.org/10.1186/s10194-016-0610-4

Andreou AP, Holland PR, Akerman S, Summ O, Fredrick J and Goadsby PJ. Transcranial magnetic stimulation and potential cortical and trigeminothalamic mechanisms in migraine. Brain 2016; 139(Pt7):2002-2014 Doi:10.1093/brain/aww118 DOI: https://doi.org/10.1093/brain/aww118

Kemp WJ, 3rd, Tubbs RS and Cohen-Gadol AA. The innervation of the cranial dura mater: neurosurgical case correlates and a review of the literature. World Neurosurg 2012;78(5):505-510 Doi:10.1016/j.wneu.2011.10.045 DOI: https://doi.org/10.1016/j.wneu.2011.10.045

Jouvet M. Neurophysiology of the states of sleep. Physiol Rev 1967;47(2):117-177 Doi:10.1152/physrev.1967.47.2.117 DOI: https://doi.org/10.1152/physrev.1967.47.2.117

Strother LC, Srikiatkhachorn A and Supronsinchai W. Targeted Orexin and Hypothalamic Neuropeptides for Migraine. Neurotherapeutics 2018;15(2):377-390 Doi:10.1007/s13311-017-0602-3 DOI: https://doi.org/10.1007/s13311-017-0602-3

Denuelle M, Fabre N, Payoux P, Chollet F and Geraud G. Hypothalamic activation in spontaneous migraine attacks. Headache 2007;47(10):1418-1426 Doi:10.1111/j.1526-4610.2007.00776.x DOI: https://doi.org/10.1111/j.1526-4610.2007.00776.x

Maniyar FH, Sprenger T, Monteith T, Schankin C and Goadsby PJ. Brain activations in the premonitory phase of nitroglycerin-triggered migraine attacks. Brain 2014;137(Pt 1):232-241 Doi:10.1093/brain/awt320 DOI: https://doi.org/10.1093/brain/awt320

Stanyer EC, Creeney H, Nesbitt AD, Holland PR and Hoffmann J. Subjective Sleep Quality and

Sleep Architecture in Patients With Migraine: A Meta-analysis. Neurology

;97(16):e1620-e1631 Doi:10.1212/wnl.0000000000012701 DOI: https://doi.org/10.1212/WNL.0000000000012701

Baksa D, Gecse K, Kumar S, Toth Z, Gal Z, Gonda X and Juhasz G. Circadian Variation of

Migraine Attack Onset: A Review of Clinical Studies. Biomed Res Int 2019;2019:4616417

Doi:10.1155/2019/4616417 DOI: https://doi.org/10.1155/2019/4616417

Song TJ, Kim BS and Chu MK. Therapeutic role of melatonin in migraine prophylaxis: Is

there a link between sleep and migraine? Prog Brain Res 2020;255:343-369

Doi:10.1016/bs.pbr.2020.05.014 DOI: https://doi.org/10.1016/bs.pbr.2020.05.014

Peres MF, Sanchez del Rio M, Seabra ML, Tufik S, Abucham J, Cipolla-Neto J, . . . Zukerman E.

Hypothalamic involvement in chronic migraine. J Neurol Neurosurg Psychiatry

;71(6):747-751 Doi:10.1136/jnnp.71.6.747 DOI: https://doi.org/10.1136/jnnp.71.6.747

Laurell K, Artto V, Bendtsen L, Hagen K, Häggström J, Linde M, . . . Kallela M. Premonitory

symptoms in migraine: A cross-sectional study in 2714 persons. Cephalalgia

;36(10):951-959 Doi:10.1177/0333102415620251 DOI: https://doi.org/10.1177/0333102415620251

Andress-Rothrock D, King W and Rothrock J. An analysis of migraine triggers in a clinic-

based population. Headache 2010;50(8):1366-1370 Doi:10.1111/j.1526-4610.2010.01753.x DOI: https://doi.org/10.1111/j.1526-4610.2010.01753.x

Bertisch SM, Li W, Buettner C, Mostofsky E, Rueschman M, Kaplan ER, . . . Mittleman MA.

Nightly sleep duration, fragmentation, and quality and daily risk of migraine. Neurology

;94(5):e489-e496 Doi:10.1212/wnl.0000000000008740 DOI: https://doi.org/10.1212/WNL.0000000000008740

Andreou AP and Edvinsson L. Mechanisms of migraine as a chronic evolutive condition. J

Headache Pain 2019;20(1):117 Doi:10.1186/s10194-019-1066-0 DOI: https://doi.org/10.1186/s10194-019-1066-0

Casteren DS, Verhagen IE, Onderwater GL, MaassenVanDenBrink A and Terwindt GM. Sex

differences in prevalence of migraine trigger factors: A cross-sectional study. Cephalalgia

;41(6):643-648 Doi:10.1177/0333102420974362 DOI: https://doi.org/10.1177/0333102420974362

Tiseo C, Vacca A, Felbush A, Filimonova T, Gai A, Glazyrina T, . . . Sacco S. Migraine and sleep

disorders: a systematic review. J Headache Pain 2020;21(1):126 Doi:10.1186/s10194-020-

-5

Kelman L. The premonitory symptoms (prodrome): a tertiary care study of 893

migraineurs. Headache 2004;44(9):865-872 Doi:10.1111/j.1526-4610.2004.04168.x DOI: https://doi.org/10.1111/j.1526-4610.2004.04168.x

Cerbo R, Barbanti P, Buzzi MG, Fabbrini G, Brusa L, Roberti C, . . . Lenzi GL. Dopamine

hypersensitivity in migraine: role of the apomorphine test. Clin Neuropharmacol

;20(1):36-41 Doi:10.1097/00002826-199702000-00004 DOI: https://doi.org/10.1097/00002826-199702000-00004

Amery WK and Waelkens J. Prevention of the last chance: an alternative pharmacologic

treatment of migraine. Headache 1983;23(1):37-38 Doi:10.1111/j.1526-

1983.hed2101037.x

Karsan N, Bose P, Newman J and Goadsby PJ. Are some patient-perceived migraine triggers

simply early manifestations of the attack? J Neurol 2021;268(5):1885-1893

Doi:10.1007/s00415-020-10344-1 DOI: https://doi.org/10.1007/s00415-020-10344-1

Walters AB, Hamer JD and Smitherman TA. Sleep disturbance and affective comorbidity

among episodic migraineurs. Headache 2014;54(1):116-124 Doi:10.1111/head.12168 DOI: https://doi.org/10.1111/head.12168

Ødegård SS, Engstrøm M, Sand T, Stovner LJ, Zwart JA and Hagen K. Associations between

sleep disturbance and primary headaches: the third Nord-Trøndelag Health Study. J

Headache Pain 2010;11(3):197-206 Doi:10.1007/s10194-010-0201-8 DOI: https://doi.org/10.1007/s10194-010-0201-8

Goel N, Rao H, Durmer JS and Dinges DF. Neurocognitive consequences of sleep

deprivation. Semin Neurol 2009;29(4):320-339 Doi:10.1055/s-0029-1237117 DOI: https://doi.org/10.1055/s-0029-1237117

Banks S and Dinges DF. Behavioral and physiological consequences of sleep restriction. J

Clin Sleep Med 2007;3(5):519-528

Killgore WD. Effects of sleep deprivation on cognition. Prog Brain Res 2010;185(105-129

Doi:10.1016/b978-0-444-53702-7.00007-5 DOI: https://doi.org/10.1016/B978-0-444-53702-7.00007-5

Schmid SM, Hallschmid M, Jauch-Chara K, Born J and Schultes B. A single night of sleep

deprivation increases ghrelin levels and feelings of hunger in normal-weight healthy men. J

Sleep Res 2008;17(3):331-334 Doi:10.1111/j.1365-2869.2008.00662.x DOI: https://doi.org/10.1111/j.1365-2869.2008.00662.x

Suzuki K, Miyamoto T, Miyamoto M, Suzuki S, Watanabe Y, Takashima R and Hirata K.

Dream-enacting behaviour is associated with impaired sleep and severe headache-related

disability in migraine patients. Cephalalgia 2013;33(10):868-878

Doi:10.1177/0333102413477742 DOI: https://doi.org/10.1177/0333102413477742

Wijeratne T, Kuan WS, Kelly AM, Chu KH, Kinnear FB, Keijzers G, . . . Laribi S. Migraine in the

Emergency Department: A Prospective Multinational Study of Patient Characteristics,

Management, and Outcomes. Neuroepidemiology 2022;56(1):32-40

Doi:10.1159/000520548 DOI: https://doi.org/10.1159/000520548

Cernuda-Morollón E, Larrosa D, Ramón C, Vega J, Martínez-Camblor P and Pascual J.

Interictal increase of CGRP levels in peripheral blood as a biomarker for chronic migraine.

Neurology 2013;81(14):1191-1196 Doi:10.1212/WNL.0b013e3182a6cb72 DOI: https://doi.org/10.1212/WNL.0b013e3182a6cb72

Voss T, Lipton RB, Dodick DW, Dupre N, Ge JY, Bachman R, . . . Michelson D. A phase IIb

randomized, double-blind, placebo-controlled trial of ubrogepant for the acute treatment

of migraine. Cephalalgia 2016;36(9):887-898 Doi:10.1177/0333102416653233 DOI: https://doi.org/10.1177/0333102416653233

Goadsby PJ and Sprenger T. Current practice and future directions in the prevention and

acute management of migraine. Lancet Neurol 2010;9(3):285-298 Doi:10.1016/s1474- DOI: https://doi.org/10.1016/S1474-4422(10)70005-3

(10)70005-3

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Published

2022-09-30

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1.
Ferreira PG, Ricardi LHB, Costa Júnior ER da, Cesar AR de A. The importance of addressing sleep disorders in migraine treatment. Headache Med [Internet]. 2022 Sep. 30 [cited 2024 Nov. 22];13(3):192-200. Available from: https://headachemedicine.com.br/index.php/hm/article/view/664

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