The association between diabetes and migraine: a systematic review and meta-analysis
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https://doi.org/10.48208/HeadacheMed.2024.42Palavras-chave:
Diabetes Mellitus, Migraine, Migraine with aura, Migraine without auraResumo
Introdução
O diabetes e a enxaqueca são condições prevalentes que podem impactar significativamente a qualidade de vida. Revisões existentes sugerem uma possível conexão entre as duas, embora os achados tenham variado.
Objetivo
Esta revisão tem como objetivo analisar e integrar as evidências sobre a associação entre diabetes e enxaqueca por meio de uma meta-análise.
Métodos
Esta abordagem foi aplicada por meio de buscas nas bases Scopus, WOS, PubMed e Google Scholar. Foi seguido um checklist PRISMA. A avaliação da qualidade foi realizada. As meta-análises foram realizadas usando Jamovi 2.3.28 e SPSS Versão 28.
Resultados
Dois grupos de estudos foram analisados. O Grupo 1 (n=8) avaliou a prevalência de enxaqueca em pacientes com diabetes. A prevalência geral de enxaqueca foi de 12% (IC 95%: 6%-17%). O diabetes tipo 2 apresentou uma prevalência de enxaqueca de 8% (IC 95%: 1%-15%), afetada significativamente pela demografia dos estudos e pela duração do diabetes. O diabetes tipo 1 mostrou uma prevalência de enxaqueca mais baixa (1%). As razões de chances indicaram uma diminuição não significativa na prevalência de enxaqueca entre os pacientes diabéticos de forma geral e uma diminuição significativa para o diabetes tipo 1.
O Grupo 2 (n=17) examinou a prevalência de diabetes entre pacientes com enxaqueca. A razão de chances geral para a prevalência de diabetes foi de 0,86 (p<0,05), indicando uma diminuição significativa. Análises específicas mostraram uma redução quase significativa na prevalência de diabetes para enxaqueca com aura (OR=0,78, p=0,05) e nenhuma diferença significativa para enxaqueca sem aura (OR≈1, p=0,95).
Conclusões
Os resultados sugerem uma prevalência geralmente mais baixa de enxaqueca entre pacientes diabéticos, particularmente aqueles com diabetes tipo 1, enquanto a prevalência de diabetes é menor entre pacientes com enxaqueca, especialmente aqueles com aura.
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Copyright (c) 2024 Heba Ramadan (Author)
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
