Characterization of adult patients with a diagnosis of migraine and osmophobia: the osmograine study
DOI:
https://doi.org/10.48208/HeadacheMed.2024.31Palavras-chave:
Osmophobia, Migraine, Central Sensitization, AllodyniaResumo
Introducción: La osmofobia está asociada a una mayor intensidad de cefalea, presencia más significativa de síntomas afetivos y aparición de alodinia cutánea.
Objetivos: Determinar las características sociodemográficas y clínicas de pacientes con enfermedad episódica y crónica asociada a osmofobia.
Métodos: estudio observacional analítico transversal, foro incluido 100 pacientes.
Resultados: 65% de los pacientes presentaban osmofobia, 64,6% de los pacientes con osmofobia presentaban encefalitis crónica y 35,4% presentaban encefalitis episódica sin diferencias estadísticamente significativas p=0,120. En cuanto a las características clínicas, el dolor pulsátil fue más frecuente en un 49%, mientras que la intensidad intensa estuvo presente en un 81%. Se encontraron relaciones estadísticamente significativas entre osmofobia y fotofobia [(95,4 vs 77,1]; p=0,005), fonofobia ([96,9 vs 74,3); p=0,001) y alodinia ([75,4 vs 45,7); p=0,002). Los factores que se vuelven crónicos son más frecuentes en el grupo con osmofobia, en el que se observó una asociación con el uso excesivo de analgésicos ([43,8% vs. 22,9%]; p=0,029) y antecedentes de ansiedad y depresión ([ 32,8% vs. 14,3%]; En el modelo multivariado, las variables asociadas a la osmofobia con diferencias estadísticamente significativas fueron fotofobia, alodinia y aplicación de toxina botulínica.
Conclusiones: En el primer estudio sobre la osmofobia a la enjaqueca en Colombia, la osmofobia es un síntoma frecuente en pacientes con enjaqueca crónica; relacionaros con marcadores de sensibilización central; También está relacionado con factores crónicos y el uso de toxina botulínica. Por lo tanto, es demostrable que la osmofobia puede prevenir el riesgo de este factor, haciendo que la enfermedad se vuelva crónica.
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Copyright (c) 2024 Brenda Benítez-Martínez, Marlon X. Cantillo-Martínez, Sandra Riveros Santoya, Nadia Proaños, Fidel Sobrino Mejia (Author)
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
