RELAÇÃO ENTRE DISTÚRBIOS GASTROINTESTINAIS E MIGRÂNEA: UMA REVISÃO INTEGRATIVA
DOI:
https://doi.org/10.48208/HeadacheMed.2024.13Palavras-chave:
Migrânea, Eixo cérebro-intestino, Enteropatias inflamatóriasResumo
Introdução
A migrânea é um tipo de cefaleia primária altamente incapacitante, com alta prevalência e sintomas que podem durar de 4 a 72 horas. Geralmente, é unilateral e pulsátil, acompanhada de náuseas, hipersensibilidade a estímulos sensoriais, vômitos e fadiga intensa, podendo ou não ser precedida por aura. Embora a fisiopatologia da migrânea não esteja completamente elucidada, vários mecanismos envolvendo o eixo cérebro-intestino podem explicar a associação entre migrânea e alterações gastrointestinais.
Objetivo
Esta revisão tem como objetivo analisar a influência dos distúrbios gastrointestinais na migrânea.
Métodos
Foi realizada uma revisão integrativa, sendo feito um levantamento de artigos nas bases de dados LILACS, PubMed e Scielo, utilizando descritores relevantes relacionados à migrânea e distúrbios gastrointestinais.
Resultados
A pesquisa encontrou 31 artigos, dos quais apenas 11 preencheram os critérios previamente estabelecidos. Todos os artigos elegíveis mostraram uma correlação entre migrânea e distúrbios gastrointestinais, com a síndrome do intestino irritável (SII) sendo a condição mais frequentemente mencionada.
Conclusão
Os distúrbios gastrointestinais influenciam a migrânea, possivelmente pelo metabolismo do triptofano e suas vias associadas. Compreender esses mecanismos pode levar a novos tratamentos. A SII é destacada entre os distúrbios associados à migrânea, sugerindo uma abordagem integrativa. Mudanças na dieta e estilo de vida, junto com medicamentos, são recomendadas. A identificação precoce de comorbidades pode facilitar uma gestão mais eficaz da migrânea. Contudo, mais pesquisas são necessárias para desenvolver tratamentos mais eficazes.
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Copyright (c) 2024 Carla Cristina Kanazawa, Juliane Soldi Malgarin, Bruno Bertoli Esmanhotto (Author)
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
