Association of altered serum glucose and lipid profiles with headaches in young women: clinical, cross-sectional study
DOI:
https://doi.org/10.48208/HeadacheMed.2023.38Palavras-chave:
Headache, Migraine, Blood Glucose, Cholesterol, Vitamin DResumo
Introdução: as dores de cabeça, incluindo enxaquecas e dores de cabeça tensionais, afetam milhões de pessoas em todo o mundo. As enxaquecas são o distúrbio neurológico mais comum, afetando cerca de 14,4% da população mundial. Sugere-se que a desregulação dos marcadores bioquímicos e as diferenças metabólicas individuais possam contribuir para as dores de cabeça. Objetivo: avaliar a frequência de cefaleias ou enxaquecas com alterações nos níveis séricos de lipídios, glicose e vitamina D em mulheres jovens. Métodos: estudo clínico, transversal, com 139 mulheres jovens, com idade mínima de 18 anos, baseado na terceira edição da Classificação Internacional de Cefaleias (ICHD-3). Foram coletadas análises antropométricas (IMC, CC, PA e PAD) e amostras de sangue para análise de vitamina D, glicemia e perfil lipídico. Resultados: a média de idade foi de 22 (+4,6) anos. Observamos associações entre cefaleia e os seguintes fatores: níveis elevados de glicose (97 mg/dL, p=0,028), colesterol total (180,4 mg/dL, p=0,002), HDL (44,2 mg/dL, p=0,017) e LDL (121,6 mg/dL, p=0,005). A maior duração das crises de cefaleia foi associada ao aumento dos níveis de glicose (97,9 mg/dL, p=0,028), colesterol total (186,8 mg/dL, p=0,05), pressão arterial diastólica (74 mmHg, p=0,038) e IMC (24,6kg/m2, p=0,024). Verificou-se que níveis elevados de glicose estão diretamente relacionados à presença de enxaqueca, principalmente naqueles com aura (105 mg/dL, p=0,034). Entretanto, não houve diferença significativa nos níveis de Vitamina D (p>0,640). Conclusão: níveis elevados de glicemia e colesterol plasmático total e suas frações parecem estar associados e podem aumentar com crises de cefaleia, principalmente enxaqueca, prolongando a duração da dor.Downloads
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Copyright (c) 2023 Karen Valério Zola, Jóvyne Karollyna Kaleski Vicente da Silva , Jonas Bernardes Lima Filho, Bruna Ribeiro Andrade Ramos, Vinicius Coralino Dos Reis Pereira, Nilva Galli, Claudio Lera Orsatti (Author)
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
