Association between attention deficit hyperactivity disorder (ADHD) and migraine: a review of observational studies

Authors

DOI:

https://doi.org/10.48208/HeadacheMed.2023.4

Keywords:

ADHD, Attention deficit disorder with hyperactivity, Migraine disorders, Headache, Neurodevelopmental disorders

Abstract

Introduction
Attention deficit hyperactivity disorder (ADHD) has been related to the presence of primary headaches. Among them, migraine presents a wide range of comorbidities shared with  ADHD, both from other psychiatric disorders and  somatic conditions.
Objective
This review proposes to describe the association between ADHD and migraine.
Methods
Based on literature research in the major medical databases and using as descriptors “Migraine Disorders” and “Attention Deficit Disorder with Hyperactivity”. Observational studies that addressed the relationship between migraine and ADHD and written only in English were included. Of the 49 articles found, only 6 met the inclusion criteria and were analyzed.
Conclusion
This review shows a possible sharing of symptoms between migraine and ADHD, requiring further studies to investigate this relationship.

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References

Association AP (2013) In Diagnostic and Statistical Manual of Mental Disorders: Diagnostic and Statistical Manual of Mental Disorders ed. 5, 991

Moffitt TE, Houts R, Asherson P, Belsky DW, Corcoran DL, Hammerle M, . . . Caspi A. Is Adult ADHD a Childhood-Onset Neurodevelopmental Disorder? Evidence From a Four-Decade Longitudinal Cohort Study. American Journal of Psychiatry 2015;172(10):967-977 Doi: 10.1176/appi.ajp.2015.14101266 DOI: https://doi.org/10.1176/appi.ajp.2015.14101266

Caye A, Rocha TB-M, Anselmi L, Murray J, Menezes AMB, Barros FC, . . . Rohde LA. Attention-Deficit/Hyperactivity Disorder Trajectories From Childhood to Young Adulthood. JAMA Psychiatry 2016;73(7):Doi: 10.1001/jamapsychiatry.2016.0383 DOI: https://doi.org/10.1001/jamapsychiatry.2016.0383

Halmøy A, Fasmer OB, Gillberg C and Haavik J. Occupational Outcome in Adult ADHD: Impact of Symptom Profile, Comorbid Psychiatric Problems, and Treatment. Journal of Attention Disorders 2009;13(2):175-187 Doi: 10.1177/1087054708329777 DOI: https://doi.org/10.1177/1087054708329777

Salem H, Vivas D, Cao F, Kazimi IF, Teixeira AL and Zeni CP. ADHD is associated with migraine: a systematic review and meta-analysis. Eur Child Adolesc Psychiatry 2018;27(3):267-277 Doi: 10.1007/s00787-017-1045-4 DOI: https://doi.org/10.1007/s00787-017-1045-4

Borg Skoglund L, Larsson H and Petrovic P. [ADHD in adults - history, epidemiology, and neuroscience]. Lakartidningen 2022;119(Doi:

Smitherman TA, Burch R, Sheikh H and Loder E. The prevalence, impact, and treatment of migraine and severe headaches in the United States: a review of statistics from national surveillance studies. Headache 2013;53(3):427-436 Doi: 10.1111/head.12074 DOI: https://doi.org/10.1111/head.12074

Attygalle UR, Hewawitharana G and Wijesinghe CJ. Migraine, attention deficit hyperactivity disorder and screen time in children attending a Sri Lankan tertiary care facility: are they associated? BMC Neurol 2020;20(1):275 Doi: 10.1186/s12883-020-01855- DOI: https://doi.org/10.1186/s12883-020-01855-5

Hansen TF, Hoeffding LK, Kogelman L, Haspang TM, Ullum H, Sorensen E, . . . Burgdorf K. Comorbidity of migraine with ADHD in adults. BMC Neurol 2018;18(1):147 Doi: 10.1186/s12883-018-1149-6 DOI: https://doi.org/10.1186/s12883-018-1149-6

Kutuk MO, Tufan AE, Guler G, Yalin OO, Altintas E, Bag HG, . . . Ozge A. Migraine and associated comorbidities are three times more frequent in children with ADHD and their mothers. Brain Dev 2018;40(10):857-864 Doi: 10.1016/j.braindev.2018.06.001 DOI: https://doi.org/10.1016/j.braindev.2018.06.001

Arruda MA, Arruda R, Guidetti V and Bigal ME. ADHD Is Comorbid to Migraine in Childhood: A Population-Based Study. J Atten Disord 2020;24(7):990-1001 Doi: 10.1177/1087054717710767 DOI: https://doi.org/10.1177/1087054717710767

Fasmer OB, Halmoy A, Oedegaard KJ and Haavik J. Adult attention deficit hyperactivity disorder is associated with migraine headaches. Eur Arch Psychiatry Clin Neurosci 2011;261(8):595-602 Doi: 10.1007/s00406-011-0203-9 DOI: https://doi.org/10.1007/s00406-011-0203-9

Arruda MA, Guidetti V, Galli F, Albuquerque RC and Bigal ME. Migraine, tension-type headache, and attention-deficit/hyperactivity disorder in childhood: a population-based study. Postgrad Med 2010;122(5):18-26 Doi: 10.3810/pgm.2010.09.2197 DOI: https://doi.org/10.3810/pgm.2010.09.2197

Villa TR, Correa Moutran AR, Sobirai Diaz LA, Pereira Pinto MM, Carvalho FA, Gabbai AA and de Souza Carvalho D. Visual attention in children with migraine: a controlled comparative study. Cephalalgia 2009;29(6):631-634 Doi: 10.1111/j.1468-2982.2008.01767.x DOI: https://doi.org/10.1111/j.1468-2982.2008.01767.x

Edden RA, Crocetti D, Zhu H, Gilbert DL and Mostofsky SH. Reduced GABA concentration in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 2012;69(7):750-753 Doi: 10.1001/archgenpsychiatry.2011.2280 DOI: https://doi.org/10.1001/archgenpsychiatry.2011.2280

Williams NM, Zaharieva I, Martin A, Langley K, Mantripragada K, Fossdal R, . . . Thapar A. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis. Lancet 2010;376(9750):1401-1408 Doi: 10.1016/S0140-6736(10)61109-9 DOI: https://doi.org/10.1016/S0140-6736(10)61109-9

Harder AV, Terwindt GM, Nyholt DR and van den Maagdenberg AM. Migraine genetics: Status and road forward. Cephalalgia 2023;43(2):3331024221145962 Doi: 10.1177/03331024221145962 DOI: https://doi.org/10.1177/03331024221145962

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Published

2023-03-31

How to Cite

1.
Fortes HMS, Andrade CL. Association between attention deficit hyperactivity disorder (ADHD) and migraine: a review of observational studies . Headache Med [Internet]. 2023 Mar. 31 [cited 2024 Dec. 22];14(1):13-7. Available from: https://headachemedicine.com.br/index.php/hm/article/view/762

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