Propranolol: A migraine prophylactic since the 1960s
DOI:
https://doi.org/10.48208/HeadacheMed.2023.2Keywords:
Beta-blocker, Propranolol, Migraine, ProphylaxisAbstract
Introduction
Propranolol was the first non-selective beta-adrenergic blocker to be developed. Initially it was used in the treatment of cardiovascular diseases, but since the 60's it has been used in the prevention of migraine.
Objective
The objective of this study was to know the history of propranolol and its use as a migraine prophylactic.
Methods
This study was an integrative literature review using articles with historical data on propranolol, from its origin in cardiology to its indication in the preventive treatment of migraine.
Results
Propranolol was described in 1962 for the treatment of cardiovascular diseases. In the same decade, it was prescribed for the preventive treatment of migraine and, recently, included in the consensus of the Brazilian Headache Society.
Conclusion
Although propranolol was initially synthesized for the treatment of heart disease, it has proved to be an effective drug in preventing migraine attacks.
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References
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Copyright (c) 2023 Wallyson Pablo de Oliveira Souza, Yasmine Maria Leódido Fortes, Adriana de Almeida Soares, Raimundo Pereira Silva-Néto
This work is licensed under a Creative Commons Attribution 4.0 International License.
