Obstructive sleep apnea and headache: an integrative review of the last 18 years

Authors

DOI:

https://doi.org/10.48208/HeadacheMed.2022.17

Keywords:

Obstructive sleep apnea, Sleep apnea headache, Morning headache, Cluster headache, Chronic headache

Abstract

Introduction

Obstructive sleep apnea (OSA) is a prevalent and underdiagnosed clinical condition, characterized by the presence of repetitive airway collapse during sleep, resulting in oxyhemoglobin desaturation and sleep fragmentation. Among the most frequent reports of patients with OSA, is morning headache or chronic daily headache, which in 2004 received its own classification in the International Classification of Headache Disorders (ICHD-2) as sleep apnea headache.

Objective

The present review aims to evaluate the available scientific literature on the association between OSA and headache after classification, totaling a period of 18 years.

Results

In 8 included studies, 1,637 patients were analyzed, observing a bilateral and frequent association between the two pathologies.

Conclusion

However, there is still no consensus on the mechanism behind this relationship, and the results of studies are divergent.

Downloads

Download data is not yet available.

References

Patel SR. Obstructive Sleep Apnea. Ann Intern Med 2019;171(11):Itc81-itc96 Doi:10.7326/aitc201912030 DOI: https://doi.org/10.7326/AITC201912030

Peppard PE, Young T, Barnet JH, Palta M, Hagen EW and Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol 2013;177(9):1006-1014 Doi:10.1093/aje/kws342 DOI: https://doi.org/10.1093/aje/kws342

Epstein LJ, Kristo D, Strollo PJ, Jr., Friedman N, Malhotra A, Patil SP, . . . Weinstein MD. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med 2009;5(3):263-276 DOI: https://doi.org/10.5664/jcsm.27497

Chung F, Subramanyam R, Liao P, Sasaki E, Shapiro C and Sun Y. High STOP-Bang score indicates a high probability of obstructive sleep apnoea. Br J Anaesth 2012;108(5):768-775 Doi:10.1093/bja/aes022 DOI: https://doi.org/10.1093/bja/aes022

Arnaud C, Bochaton T, Pépin JL and Belaidi E. Obstructive sleep apnoea and cardiovascular consequences: Pathophysiological mechanisms. Arch Cardiovasc Dis 2020;113(5):350-358 Doi:10.1016/j.acvd.2020.01.003 DOI: https://doi.org/10.1016/j.acvd.2020.01.003

Lévy P, Kohler M, McNicholas WT, Barbé F, McEvoy RD, Somers VK, . . . Pépin JL. Obstructive sleep apnoea syndrome. Nat Rev Dis Primers 2015;1:15015 Doi:10.1038/nrdp.2015.15 DOI: https://doi.org/10.1038/nrdp.2015.15

Stark CD and Stark RJ. Sleep and chronic daily headache. Curr Pain Headache Rep 2015;19(1):468 Doi:10.1007/s11916-014-0468-6 DOI: https://doi.org/10.1007/s11916-014-0468-6

Ferini-Strambi L, Galbiati A and Combi R. Sleep disorder-related headaches. Neurol Sci 2019;40(Suppl 1):107-113 Doi:10.1007/s10072-019-03837-z DOI: https://doi.org/10.1007/s10072-019-03837-z

Jennum P and Jensen R. Sleep and headache. Sleep Med Rev 2002;6(6):471-479 Doi:10.1053/smrv.2001.0223 DOI: https://doi.org/10.1053/smrv.2001.0223

Song TJ, Lee MJ, Choi YJ, Kim BK, Chung PW, Park JW, . . . Cho SJ. Differences in Characteristics and Comorbidity of Cluster Headache According to the Presence of Migraine. J Clin Neurol 2019;15(3):334-338 Doi:10.3988/jcn.2019.15.3.334 DOI: https://doi.org/10.3988/jcn.2019.15.3.334

The International Classification of Headache Disorders: 2nd edition. Cephalalgia 2004;24 Suppl 1:9-160 Doi:10.1111/j.1468-2982.2003.00824.x DOI: https://doi.org/10.1111/j.1468-2982.2003.00824.x

KoÇ G, Metİn KM, AkÇay BD, KaradaŞ Ö, Sayin R and Yetkİn S. Relationship between Apnea-Hypopnea Index and Oxygen Desaturation in REM-Sleep Period and Morning Headache in Patients with Obstructive Sleep Apnea Syndrome. Noro Psikiyatr Ars 2020;57(4):294-298 Doi:10.29399/npa.23348 DOI: https://doi.org/10.29399/npa.23348

Kristiansen HA, Kværner KJ, Akre H, Øverland B, Sandvik L and Russell MB. Sleep apnoea headache in the general population. Cephalalgia 2012;32(6):451-458 Doi:10.1177/0333102411431900 DOI: https://doi.org/10.1177/0333102411431900

Alberti A, Mazzotta G, Gallinella E and Sarchielli P. Headache characteristics in obstructive sleep apnea syndrome and insomnia. Acta Neurol Scand 2005;111(5):309-316 Doi:10.1111/j.1600-0404.2005.00372.x DOI: https://doi.org/10.1111/j.1600-0404.2005.00372.x

Spałka J, Kędzia K, Kuczyński W, Kudrycka A, Małolepsza A, Białasiewicz P and Mokros Ł. Morning Headache as an Obstructive Sleep Apnea-Related Symptom among Sleep Clinic Patients-A Cross-Section Analysis. Brain Sci 2020;10(1):Doi:10.3390/brainsci10010057 DOI: https://doi.org/10.3390/brainsci10010057

Chen PK, Fuh JL, Lane HY, Chiu PY, Tien HC and Wang SJ. Morning headache in habitual snorers: frequency, characteristics, predictors and impacts. Cephalalgia 2011;31(7):829-836 Doi:10.1177/0333102411403635 DOI: https://doi.org/10.1177/0333102411403635

Mitsikostas DD, Vikelis M and Viskos A. Refractory chronic headache associated with obstructive sleep apnoea syndrome. Cephalalgia 2008;28(2):139-143 Doi:10.1111/j.1468-2982.2007.01473.x DOI: https://doi.org/10.1111/j.1468-2982.2007.01473.x

Nobre ME, Leal AJ and Filho PM. Investigation into sleep disturbance of patients suffering from cluster headache. Cephalalgia 2005;25(7):488-492 Doi:10.1111/j.1468-2982.2004.00897.x DOI: https://doi.org/10.1111/j.1468-2982.2004.00897.x

Graff-Radford SB and Newman A. Obstructive sleep apnea and cluster headache. Headache 2004;44(6):607-610 Doi:10.1111/j.1526-4610.2004.446010.x DOI: https://doi.org/10.1111/j.1526-4610.2004.446010.x

The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013;33(9):629-808 Doi:10.1177/0333102413485658 DOI: https://doi.org/10.1177/0333102413485658

May A, Schwedt TJ, Magis D, Pozo-Rosich P, Evers S and Wang SJ. Cluster headache. Nat Rev Dis Primers 2018;4:18006 Doi:10.1038/nrdp.2018.6 DOI: https://doi.org/10.1038/nrdp.2018.6

Downloads

Published

2022-09-30

How to Cite

1.
Fortes HMS, Severiano RSD, Barros PP, Silva BM da C, Freitas LL, Sena A dos S, Roberto RP. Obstructive sleep apnea and headache: an integrative review of the last 18 years. Headache Med [Internet]. 2022 Sep. 30 [cited 2024 Dec. 21];13(3):174-8. Available from: https://headachemedicine.com.br/index.php/hm/article/view/654

Issue

Section

Review

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)