Headache and neuroimaging findings in conditions of cerebrospinal fluid (CSF) circulation disorders: in hydrocephalus, pseudotumor cerebri, and CSF hypotension syndrome

Authors

DOI:

https://doi.org/10.48208/HeadacheMed.2021.47

Keywords:

Post-Dural Puncture Headache, Intracranial Hypotension, Neuroimaging, Pseudotumor Cerebri, Headache

Abstract

The authors wish in this narrative minireview show and comment on some neuroimaging findings encountered in patients with conditions of cerebrospinal fluid circulation disorders, such as in the hydrocephalus, pseudotumor cerebri, and CSF hypotension syndrome. The MRI of a young woman with a clinical diagnosis of post-dural puncture headache, performed on the fourth postpartum day after cesarean delivery, evolving with headache and diplopia, is shown. Non-contrast-enhanced sagittal T1 magnetic resonance imaging shows that the cerebellar tonsils are at the level of the foramen magnum, therefore still within normal limits, but, despite that, the opening of the cerebral aqueduct in the third ventricle is below the imaginary line connecting the anterior clinoid to the vein of Galen, therefore considered abnormally lower than the expected anatomical position. The axial T1-weighted images with post-contrast fat suppression also show impregnation and thickening of the dura mater. There is also mild engorgement of the cerebral venous sinuses, best demonstrated on T1 with post-contrast fat suppression, which is also identified on post-contrast magnetic resonance angiography, with no signs of venous thrombosis. We conclude that the diagnosis of a patient with intracranial hypotension syndrome can be suspected or confirmed with typical neuroimaging findings.

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References

Stern WE. Intracranial Fluid Dynamics: The Relationship of Intracranial Pressure to the Monro-Kellie Doctrine and the Reliability of Pressure Assessment. J R Coll Surg Edinb 1963; 9(18-36)

Mokri B. The Monro-Kellie hypothesis: applications in CSF volume depletion. Neurology 2001; 56(12):1746-1748 Doi:10.1212/wnl.56.12.1746 DOI: https://doi.org/10.1212/WNL.56.12.1746

Neff S and Subramaniam RP. Monro-Kellie doctrine. J Neurosurg 1996; 85(6):1195 DOI: https://doi.org/10.3171/jns.1996.85.6.1195

Greitz D, Wirestam R, Franck A, Nordell B, Thomsen C and Stahlberg F. Pulsatile brain movement and associated hydrodynamics studied by magnetic resonance phase imaging. The Monro-Kellie doctrine revisited. Neuroradiology 1992; 34(5):370-380 Doi:10.1007/BF00596493 DOI: https://doi.org/10.1007/BF00596493

Macintyre I. A hotbed of medical innovation: George Kellie (1770-1829), his colleagues at Leith and the Monro-Kellie doctrine. J Med Biogr 2014; 22(2):93-100 Doi:10.1177/09677720134792710967772013479271 [pii] DOI: https://doi.org/10.1177/0967772013479271

Wilson MH. Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure. J Cereb Blood Flow Metab 2016; 36(8):1338-1350 Doi:10.1177/0271678X166487110271678X16648711 [pii] DOI: https://doi.org/10.1177/0271678X16648711

Kalisvaart ACJ, Wilkinson CM, Gu S, Kung TFC, Yager J, Winship IR, . . .Colbourne F. An update to the Monro-Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke. Sci Rep 2020; 10(1):22013 Doi:10.1038/s41598-020-78880-410.1038/s41598-020-78880-4 [pii] DOI: https://doi.org/10.1038/s41598-020-78880-4

Dobrocky T, Rebsamen M, Rummel C, Hani L, Mordasini P, Raabe A, . . .Beck J. Monro-Kellie Hypothesis: Increase of Ventricular CSF Volume after Surgical Closure of a Spinal Dural Leak in Patients with Spontaneous Intracranial Hypotension. AJNR Am J Neuroradiol 2020; 41(11):2055-2061 Doi:10.3174/ajnr.A678241/11/2055 [pii] DOI: https://doi.org/10.3174/ajnr.A6782

Wu JW, Wang YF, Hseu SS, Chen ST, Chen YL, Wu YT, . . .Wang SJ. Brain volume changes in spontaneous intracranial hypotension: Revisiting the Monro-Kellie doctrine. Cephalalgia 2021; 41(1):58-68 Doi:10.1177/0333102420950385 DOI: https://doi.org/10.1177/0333102420950385

Mangalore S, Rakshith S and Srinivasa R. Solving the Riddle of "Idiopathic" in Idiopathic Intracranial Hypertension and Normal Pressure Hydrocephalus: An Imaging Study of the Possible Mechanisms - Monro-Kellie 3.0. Asian J Neurosurg 2019; 14(2):440-452 Doi:10.4103/ajns.AJNS_252_18AJNS-14-440 [pii] DOI: https://doi.org/10.4103/ajns.AJNS_252_18

Carroll C and Riddle M. Nonspecific Headache Diagnosed as a Brain Colloid Cyst with Hydrocephalus. Clin Pract Cases Emerg Med 2017; 1(2):84-86 Doi:10.5811/cpcem.2016.12.32939cpcem-01-84 [pii] DOI: https://doi.org/10.5811/cpcem.2016.12.32939

Yigit M, Seyithanoglu MH, Dundar TT, Sogut O and Yigit E. A Rare Cause of Headache in the Emergency Department: Intraventricular Epidermoid Cyst Rupture With Hydrocephalus. J Clin Med Res 2016; 8(7):560-561 Doi:10.14740/jocmr2585w DOI: https://doi.org/10.14740/jocmr2585w

Titlic M, Jukic I, Kolic K, Rogosic V and Josipovic-Jelic Z. An acute headache and hydrocephalus caused by the dermoid cyst. Bratisl Lek Listy 2008; 109(12):580-581

Fitt GJ. Headache and hydrocephalus. Aust Fam Physician 1998; 27(3):194-195

Valença MM, Farias HSSd, Almeida LCA, França CLdS, Nobre KEL, Valença MA, . . .Valença LPAdA. Headache as a single clinical manifestation of a colloid cyst in the third ventricle. Headache Medicine 2017; 8(1):25 Doi:10.48208/HeadacheMed.2017.7 DOI: https://doi.org/10.48208/HeadacheMed.2017.7

Burkett JG and Ailani J. An Up to Date Review of Pseudotumor Cerebri Syndrome. Curr Neurol Neurosci Rep 2018; 18(6):33 Doi:10.1007/s11910-018-0839-110.1007/s11910-018-0839-1 [pii] DOI: https://doi.org/10.1007/s11910-018-0839-1

Cazzo E, Gestic MA, Utrini MP, Mendonca Chaim FD, Mendonca Chaim FH, Candido EC, . . .Chaim EA. Bariatric surgery as a treatment for pseudotumor cerebri: case study and narrative review of the literature. Sao Paulo Med J 2018; 136(2):182-187 Doi:S1516-31802017005007103 [pii]10.1590/1516-3180.2016.0305060117 DOI: https://doi.org/10.1590/1516-3180.2016.0305060117

Parker JR and Parker JC, Jr. Pseudotumor cerebri: a review. Ann Clin Lab Sci 1993; 23(5):325-328

Mahajnah M, Genizi J, Zahalka H, Andreus R and Zelnik N. Pseudotumor Cerebri Syndrome: From Childhood to Adulthood Risk Factors and Clinical Presentation. J Child Neurol 2020; 35(5):311-316 Doi:10.1177/0883073819895179 DOI: https://doi.org/10.1177/0883073819895179

Hamedani AG, Witonsky KFR, Cosico M, Rennie R, Xiao R, Sheldon CA, . . .Szperka CL. Headache Characteristics in Children With Pseudotumor Cerebri Syndrome, Elevated Opening Pressure Without Papilledema, and Normal Opening Pressure: A Retrospective Cohort Study. Headache 2018; 58(9):1339-1346 Doi:10.1111/head.13362 DOI: https://doi.org/10.1111/head.13362

Mallery RM, Friedman DI and Liu GT. Headache and the pseudotumor cerebri syndrome. Curr Pain Headache Rep 2014; 18(9):446 Doi:10.1007/s11916-014-0446-z DOI: https://doi.org/10.1007/s11916-014-0446-z

Friedman DI. Pseudotumor cerebri presenting as headache. Expert Rev Neurother 2008; 8(3):397-407 Doi:10.1586/14737175.8.3.397 DOI: https://doi.org/10.1586/14737175.8.3.397

Chisholm JT, Abou-Jaoude MM, Hessler AB and Sudhakar P. Pseudotumor Cerebri Syndrome with Resolution After Discontinuing High Vitamin A Containing Dietary Supplement: Case Report and Review. Neuroophthalmology 2018; 42(3):169-175 Doi:10.1080/01658107.2017.13679311367931 [pii] DOI: https://doi.org/10.1080/01658107.2017.1367931

Dotan G, Goldstein M, Stolovitch C and Kesler A. Pediatric Pseudotumor Cerebri Associated With Low Serum Levels of Vitamin A. J Child Neurol 2013; 28(11):1370-1377 Doi:0883073812474344 [pii]10.1177/0883073812474344 DOI: https://doi.org/10.1177/0883073812474344

Morrice G, Jr., Havener WH and Kapetansky F. Vitamin A intoxication as a cause of pseudotumor cerebri. JAMA 1960; 173(1802-1805 Doi:10.1001/jama.1960.03020340020005 DOI: https://doi.org/10.1001/jama.1960.03020340020005

Selhorst JB, Waybright EA, Jennings S and Corbett JJ. Liver lover's headache: pseudotumor cerebri and vitamin A intoxication. JAMA 1984; 252(24):3365 DOI: https://doi.org/10.1001/jama.1984.03350240015014

Morris PP, Black DF, Port J and Campeau N. Transverse Sinus Stenosis Is the Most Sensitive MR Imaging Correlate of Idiopathic Intracranial Hypertension. AJNR Am J Neuroradiol 2017; 38(3):471-477 Doi:10.3174/ajnr.A5055 DOI: https://doi.org/10.3174/ajnr.A5055

ajnr.A5055 [pii]

Akay R, Kamisli O, Kahraman A, Oner S and Tecellioglu M. Evaluation of aqueductal CSF flow dynamics with phase contrast cine MR imaging in idiopathic intracranial hypertension patients: preliminary results. Eur Rev Med Pharmacol Sci 2015; 19(18):3475-3479 Doi:9534 [pii]

Shofty B, Ben-Sira L, Constantini S, Freedman S and Kesler A. Optic nerve sheath diameter on MR imaging: establishment of norms and comparison of pediatric patients with idiopathic intracranial hypertension with healthy controls. AJNR Am J Neuroradiol 2012; 33(2):366-369 Doi:10.3174/ajnr.A2779ajnr.A2779 [pii] DOI: https://doi.org/10.3174/ajnr.A2779

Suzuki H, Takanashi J, Kobayashi K, Nagasawa K, Tashima K and Kohno Y. MR imaging of idiopathic intracranial hypertension. AJNR Am J Neuroradiol 2001; 22(1):196-199

Yuh WT, Zhu M, Taoka T, Quets JP, Maley JE, Muhonen MG, . . .Kardon RH. MR imaging of pituitary morphology in idiopathic intracranial hypertension. J Magn Reson Imaging 2000; 12(6):808-813 Doi:10.1002/1522-2586(200012)12:6<808::AID-JMRI3>3.0.CO;2-N [pii]10.1002/1522-2586(200012)12:6<808::aid-jmri3>3.0.co;2-n

Gideon P, Thomsen C, Gjerris F, Sorensen PS, Stahlberg F and Henriksen O. Measurement of blood flow in the superior sagittal sinus in healthy volunteers, and in patients with normal pressure hydrocephalus and idiopathic intracranial hypertension with phase-contrast cine MR imaging. Acta Radiol 1996; 37(2):171-176 Doi:10.1177/02841851960371P135 DOI: https://doi.org/10.1080/02841859609173439

George AE. Idiopathic intracranial hypertension: pathogenesis and the role of MR imaging. Radiology 1989; 170(1 Pt 1):21-22 Doi:10.1148/radiology.170.1.2909099 DOI: https://doi.org/10.1148/radiology.170.1.2909099

Degnan AJ and Levy LM. Pseudotumor cerebri: brief review of clinical syndrome and imaging findings. AJNR Am J Neuroradiol 2011; 32(11):1986-1993 Doi:10.3174/ajnr.A2404ajnr.A2404 [pii] DOI: https://doi.org/10.3174/ajnr.A2404

Amorim JA, Gomes de Barros MV and Valenca MM. Post-dural (post-lumbar) puncture headache: risk factors and clinical features. Cephalalgia 2012; 32(12):916-923 Doi:10.1177/03331024124539510333102412453951 [pii] DOI: https://doi.org/10.1177/0333102412453951

Valenca MM, Amorim JA and Moura TP. Why don't all individuals who undergo dura mater/arachnoid puncture develop postdural puncture headache? Anesth Pain Med 2012; 1(3):207-209 Doi:10.5812/kowsar.22287523.3616 DOI: https://doi.org/10.5812/aapm.3616

Huang YM and Davidsson L. Sagging brain development after lumbar puncture agrees with Monro-Kellie hypothesis. J Neurol 2013; 260(3):920-922 Doi:10.1007/s00415-012-6811-0 DOI: https://doi.org/10.1007/s00415-012-6811-0

George U, Rathore S, Pandian JD and Singh Y. Diffuse pachymeningeal enhancement and subdural and subarachnoid space opacification on delayed postcontrast fluid-attenuated inversion recovery imaging in spontaneous intracranial hypotension: visualizing the Monro-Kellie hypothesis. AJNR Am J Neuroradiol 2011; 32(1):E16 Doi:10.3174/ajnr.A2262ajnr.A2262 [pii] DOI: https://doi.org/10.3174/ajnr.A2262

Shobeiri E and Torabinejad B. Brain magnetic resonance imaging findings in postpartum headache. Neuroradiol J 2019; 32(1):4-9 Doi:10.1177/1971400918804193 DOI: https://doi.org/10.1177/1971400918804193

Alves AR, Queijo JC, Goncalves LM and Lima MH. A differential diagnosis for a postpartum headache. J Clin Anesth 2022; 77(110624 Doi:S0952-8180(21)00467-0 [pii]10.1016/j.jclinane.2021.110624 DOI: https://doi.org/10.1016/j.jclinane.2021.110624

Nikouline A and Carr D. Postpartum headache: A broader differential. Am J Emerg Med 2021; 39(258 e255-258 e256 Doi:S0735-6757(20)30615-X [pii]10.1016/j.ajem.2020.07.022 DOI: https://doi.org/10.1016/j.ajem.2020.07.022

Di Paolo M, Maiese A, Mangiacasale O, Pesetti B, Pierotti S, Manetti AC, . . .Turillazzi E. Don't Forget Rare Causes of Postpartum Headache! Cases Report and Literature Review. Medicina (Kaunas) 2021; 57(4):Doi:376 [pii] DOI: https://doi.org/10.3390/medicina57040376

3390/medicina57040376medicina57040376 [pii]

Serva WA, Serva VM, de Fatima Costa Caminha M, Figueiroa JN, Albuquerque EC, Serva GB, . . .Valenca MM. Course of migraine during pregnancy among migraine sufferers before pregnancy. Arq Neuropsiquiatr 2011; 69(4):613-619 Doi:S0004-282X2011000500008 [pii]10.1590/s0004-282x2011000500008 DOI: https://doi.org/10.1590/S0004-282X2011000500008

Serva WA, Serva VM, Caminha Mde F, Figueiroa JN, Serva GB and Valenca MM. Exclusive breastfeeding protects against postpartum migraine recurrence attacks? Arq Neuropsiquiatr 2012; 70(6):428-434 Doi:S0004-282X2012000600009 [pii]10.1590/s0004-282x2012000600009 DOI: https://doi.org/10.1590/S0004-282X2012000600009

Amorim JA and Valenca MM. Postdural puncture headache is a risk factor for new postdural puncture headache. Cephalalgia 2008; 28(1):5-8 Doi:CHA1454 [pii]10.1111/j.1468-2982.2007.01454.x DOI: https://doi.org/10.1111/j.1468-2982.2007.01454.x

Amorim JA, Remigio DS, Damazio Filho O, de Barros MA, Carvalho VN and Valenca MM. Intracranial subdural hematoma post-spinal anesthesia: report of two cases and review of 33 cases in the literature. Rev Bras Anestesiol 2010; 60(6):620-629, 344-629 Doi:10.1016/S0034-7094(10)70077-5S0034-7094(10)70077-5 [pii] DOI: https://doi.org/10.1016/S0034-7094(10)70077-5

Oh MK, Ryu JH, Jeon WJ, Lee CW and Cho SY. Case report: postpartum cerebral venous thrombosis misdiagnosed as postdural puncture headache. BMC Anesthesiol 2020; 20(1):80 Doi:10.1186/s12871-020-00992-110.1186/s12871-020-00992-1 [pii] DOI: https://doi.org/10.1186/s12871-020-00992-1

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2022-03-24

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Aragão M de FVV, Araújo LC, Valença MM. Headache and neuroimaging findings in conditions of cerebrospinal fluid (CSF) circulation disorders: in hydrocephalus, pseudotumor cerebri, and CSF hypotension syndrome. Headache Med [Internet]. 2022 Mar. 24 [cited 2024 Dec. 3];12(4):287-92. Available from: https://headachemedicine.com.br/index.php/hm/article/view/603

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