The diverse use of cannabis derivatives in the treatment of chronic pain




Medicinal cannabis, Cannabidiol, THC, Chronic pain


Chronic pain is a pathology that affects thousands of people annually, resulting from different factors and having different etiologies. Several treatments are available today for it, but some cases are still refractory.
This article seeks to highlight the impacts of using cannabis derivatives as an alternative in the treatment of chronic pain.
This is a bibliographic review that used the PubMed and Scopus databases to search for and select articles on the use of cannabis derivatives in the treatment of chronic pain. Only clinical trials, cohort studies, case-control studies, and case reports were selected.
336 articles were found, after applying the inclusion and exclusion criteria, 7 articles were selected to be analyzed, of which 3 used vaporized formulations, 3 used compounds for oral ingestion and 1 analyzed topical use.
Good efficiency was observed in the use of cannabis derivatives in the treatment of chronic pain, especially compounds rich in delta-9-tetrahydrocannabidiol (THC).


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How to Cite

Ferreira Marques LF, Dutra AL de A, Zafalon B, Fernandes E de BD, Pachá DP, Espíndola RS. The diverse use of cannabis derivatives in the treatment of chronic pain. Headache Med [Internet]. 2024 Jun. 30 [cited 2024 Jul. 14];15(2):72-7. Available from: