Fibromigraine: A cohort study retrospective




Migraine, Fibromyalgia, Fibromigraine, Depression, Quality of life


To diagnose fibromyalgia in patients with migraine and assess the quality of life of these patients.
Patients and Methods
A prospective, cross-sectional study was carried out, comparing groups, in a non-randomized sample, consisting of patients diagnosed with migraine. The sample was evaluated using the Widespread Pain Index (WPI) and Symptom Severity Scale (SSS) questionnaires to diagnose fibromyalgia. Quality of life and level of depression were assessed, respectively, using the Headache Impact Test-6 (HIT-6) and Patient Health Questionnaire-9 (PHQ-9).
We interviewed 100 patients (5 men and 95 women) diagnosed with migraine, with a mean age of 37.1±11.0 years, ranging from 19 to 64 years. Thirty-four patients (34%) had migraine and fibromyalgia concomitantly. Migraine predominated in females, both in the presence and absence of fibromyalgia. In both groups, there was no difference in headache characteristics. In the group with fibromyalgia, there was a predominance of allodynia and a higher PHQ-9 score (p<0.001).
Patients with migraine are more predisposed to depression when there is an association with fibromyalgia.


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How to Cite

Leódido-Fortes YM, Souza WP de, Soares A, Silva-Néto R. Fibromigraine: A cohort study retrospective. Headache Med [Internet]. 2024 Mar. 26 [cited 2024 Jun. 23];15(1):13-7. Available from:




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