Magnesium ion serum profile in chronic migraine: comparative study between treated and non-treated patients

Authors

  • Alan Chester Feitosa de Jesus Universidade Federal de Sergipe Author
  • Giselle Melo Fontes Silva Hospital Universitário Pedro Ernesto – UERJ Author
  • Marcelo Oliveira Ribeiro Paixão Universidade Estadual Paulista Author
  • Felipe José Nascimento Barreto Universidade Federal de Sergipe Author
  • Luana Karla Braz Fonseca Dantas Universidade Federal de Sergipe Author
  • Philippe Joaquim Oliveira Menezes Macedo Universidade Federal de Sergipe Author
  • Paulo Sérgio Faro Santos Universidade Federal de Sergipe Author
  • Larissy Lima Santos Universidade Federal de Sergipe Author
  • Marco Antônio Prado Nunes Universidade Federal de Sergipe Author

DOI:

https://doi.org/10.48208/HeadacheMed.2012.4

Keywords:

Chronic migraine, Serum magnesium, Pathophysiology

Abstract

Chronic migraine is recognized as a migraine complication and is characterized by frequency of attacks up to 15 days/ month for more than three months, in absence of painkiller abusive usage. Studies indicate that magnesium ion plays a role in migraine pathophysiology but, until now, they have never included only patients with chronic migraine as their population. Objective: To compare serum magnesium levels etween treated and non-treated chronic migraineurs. Methods: Twenty-two patients with chronic migraine were selected and divided in two groups (treated and non-treated), matched by sex and age, and submitted to serum dosage of magnesium ion for latter comparison. Result: The non-treated chronic migraineurs presented serum magnesium ion level within normal limits, but lower than those found in the treated group with a statistically significant difference. Conclusion: Similarly to other studies in the literature, this study stresses the importance of magnesium ion in the migraine pathophysiology, but studying only the chronic migraine patients. 

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Author Biographies

  • Alan Chester Feitosa de Jesus, Universidade Federal de Sergipe

    Neurologist, Collaborating Professor, Department of Medicine, Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

  • Giselle Melo Fontes Silva, Hospital Universitário Pedro Ernesto – UERJ

    Neurologist, Hospital Universitário Pedro Ernesto – UERJ, Rio de Janeiro, RJ, Brazil

  • Marcelo Oliveira Ribeiro Paixão, Universidade Estadual Paulista

    Neurologist, Universidade Estadual Paulista “Júlio de Mesquita Flho” – UNESP, Botucatu, SP, Brazil

  • Felipe José Nascimento Barreto, Universidade Federal de Sergipe

    Medical Doctors, Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

  • Luana Karla Braz Fonseca Dantas, Universidade Federal de Sergipe

    Medical Doctors, Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

  • Philippe Joaquim Oliveira Menezes Macedo, Universidade Federal de Sergipe

    Medical Doctors, Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

  • Paulo Sérgio Faro Santos, Universidade Federal de Sergipe

    Medical Students, Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

  • Larissy Lima Santos, Universidade Federal de Sergipe

    Medical Students, Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

  • Marco Antônio Prado Nunes, Universidade Federal de Sergipe

    Head of the Department of Medicine, Assistant Professor of Surgical Clinic of the Department of Medicine,
    Universidade Federal de Sergipe – UFS, Aracaju, SE, Brazil

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Published

2012-03-31

Issue

Section

Original

How to Cite

1.
Magnesium ion serum profile in chronic migraine: comparative study between treated and non-treated patients. Headache Med [Internet]. 2012 Mar. 31 [cited 2026 Jan. 22];3(1):21-5. Available from: https://headachemedicine.com.br/hm/article/view/310