The role of diet in migraine control: deconstructing myths
DOI:
https://doi.org/10.48208/HeadacheMed.2024.43Keywords:
Migraine , Food triggers, Nutritional supplementation, Diet therapyAbstract
Introduction: Migraine can be controlled through effective drug treatments, both during headache attacks, as a preventative measure, but also through non-drug treatments, including diet therapy. This treatment consists of eliminating food triggers and adding improvement factors.
Objective: To address the role of diet in controlling migraine, through the elimination of food triggers and the addition of improvement factors, in addition to demystifying some mistaken behaviors.
Method: This study was an integrative and retrospective review of articles on the relationship between food and migraine.
Results: Three relationships were found between diet and migraine attacks: 1) food may be a triggering factor; 2) food may be a mitigating factor; or 3) food may be an aggravating factor. There is no specific diet therapy for migraine, but diets that are based on the pathophysiological mechanisms of migraine.
Conclusions: Food can be a trigger or a factor in improving migraine attacks and diet therapy for controlling migraine consists of removing food triggers and replacing them with a healthy diet.
Downloads
References
Krymchantowski AV. Naproxen sodium decreases migraine recurrence when administered with sumatriptan. Arq Neuropsiquiatr. 2000;58(2B):428-430 Doi: https://doi.org/10.1590/S0004-282X2000000300006. DOI: https://doi.org/10.1590/S0004-282X2000000300006
Melhado EM, Santos PSF, Kaup AO, Costa ATNM, Roesler CAP, Piovesan EJ, ... and Fragoso YD. Consensus of the Brazilian Headache Society (SBCe) for prophylactic treatment of episodic migraine: part I. Arq Neuropsiquiatr. 2022;80(8):845-861. https://doi.org/doi:10.1055/s-0042-1756441. DOI: https://doi.org/10.1055/s-0042-1756441
Gazerani P. Migraine and diet. Nutrients. 2020;12(6):1658 Doi: https://doi.org/10.3390/nu12061658. DOI: https://doi.org/10.3390/nu12061658
Silva-Néto RP, Soares AA and Almeida KJ. Headache and nutrition. Headache Medicine. 2009;12(1):20-24.
Martin VT, Behbehani MM. Toward a rational understanding of migraine trigger factors. Med Clin North Am. 2001;85(4):911-941 Doi: https://doi.org/10.1016/S0025-7125(05)70351-5. DOI: https://doi.org/10.1016/S0025-7125(05)70351-5
Iba C, Ohtani S, Lee MJ, Huh S, Watanabe N, Nakahara J, … and Takizawa T. Migraine triggers in Asian countries: A narrative review. Front Neurol. 2023:14:1169795 Doi: https://doi.org/10.3389/fneur.2023.1169795. DOI: https://doi.org/10.3389/fneur.2023.1169795
Hindiyeh NA, Zhang N, Farrar M, Banerjee P, Lombard L and Aurora SK. The role of diet and nutrition in migraine triggers and treatment: A systematic literature review. Headache. 2020;60(7):1300-1316 Doi: https://doi.org/10.1111/head.13836. DOI: https://doi.org/10.1111/head.13836
Fila M, Chojnacki C, Chojnacki J and Blasiak J. Is an “epigenetic diet” for migraines justified? The case of folate and DNA methylation. Nutrients. 2019;11(11):2763 Doi: https://doi.org/10.3390/nu11112763. DOI: https://doi.org/10.3390/nu11112763
Silva-Néto RP, Rodrigues ÂB, Cavalcante DC, Ferreira PH, Nasi EP, Sousa KM, ... and Valença MM. May headache triggered by odors be regarded as a differentiating factor between migraine and other primary headaches? Cephalalgia. 2017;37(1):20-28 Doi: https://doi.org/10.1177/0333102416636098. DOI: https://doi.org/10.1177/0333102416636098
Silva-Néto RP, Bezerra GL, Araújo NRA, Silva SF, Pereira SKS, Lima LKF, ... and Lopes LS. Migraine attacks triggered by ingestion of watermelon. Eur Neurol. 2023;86(4):250-255 Doi: https://doi.org/10.1159/000531286. DOI: https://doi.org/10.1159/000531286
Martin VT and Vij B. Diet and headache: Part 1. Headache. 2016;56(6):1543-1552 Doi: https://doi.org/10.1111/head.12953. DOI: https://doi.org/10.1111/head.12953
Doulberis M, Saleh C and Beyenburg S. Is there an association between migraine and gastrointestinal disorders? J Clin Neurol. 2017;13(3):215-226 Doi: https://doi.org/10.3988/jcn.2017.13.3.215. DOI: https://doi.org/10.3988/jcn.2017.13.3.215
Ma Q, Xing C, Long W, Wang HY, Liu Q and Wang RF. Impact of microbiota on central nervous system and neurological diseases: The gut-brain axis. J Neuroinflamm. 2019;16(1):53 Doi: https://doi.org/10.1186/s12974-019-1434-3. DOI: https://doi.org/10.1186/s12974-019-1434-3
Arzani M, Jahromi SR, Ghorbani Z, Vahabizad F, Martelletti P, Ghaemi A, … and Togha M. Gut-brain Axis and migraine headache: a comprehensive review. J Headache Pain. 2020;21(1):15 Doi: https://doi.org/10.1186/s10194-020-1078-9. DOI: https://doi.org/10.1186/s10194-020-1078-9
Levis AA, Caverni CN, Wille J and Santos PSF. The relationship between the gut-brain axis and migraine. Headache Medicine 2024,15(3):119-122 Doi: https://doi.org/10.48208/HeadacheMed.2024.26. DOI: https://doi.org/10.48208/HeadacheMed.2024.26
Jahromi SR, Ghorbani Z, Martelletti P, Lampl C, Togha M and School of Advanced Studies of the European Headache Federation (EHF-SAS). Association of diet and headache. J Headache Pain. 2019;20(1):106-111 Doi: https://doi.org/10.1186/s10194-019-1057-1. DOI: https://doi.org/10.1186/s10194-019-1057-1
Haghdoost F and Togha M. Migraine management: Non-pharmacological points for patients and health care professionals. Open Med (Wars). 2022;17(1):1869-1882 Doi: https://doi.org/10.1515/med-2022-0598. DOI: https://doi.org/10.1515/med-2022-0598
Kernick D. Migraine: new Perspectives from Chaos Theory. Cephalalgia. 2005:25(8):561-566 Doi: https://doi.org/10.1111/j.1468-2982.2005.00934.x. DOI: https://doi.org/10.1111/j.1468-2982.2005.00934.x
Alpay K, Ertas M, Orhan EK, Ustay DK, Lieners C and Baykan B. Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomized, cross-over trial. Cephalalgia. 2010;30(7):829-837 Doi: https://doi.org/10.1177/0333102410361404. DOI: https://doi.org/10.1177/0333102410361404
Yuan H and Silberstein SD. Histamine and migraine. Headache. 2018;58(1):184-193 Doi: https://doi.org/10.1111/head.13164. DOI: https://doi.org/10.1111/head.13164
Verrotti A, Agostinelli S, D'Egidio C, Di Fonzo A, Carotenuto M, Parisi P, ... and Battistella PA. Impact of a weight loss program on migraine in obese adolescents. Eur J Neurol. 2012;20(2):394-397 Doi: https://doi.org/10.1111/j.1468-1331.2012.03771.x. DOI: https://doi.org/10.1111/j.1468-1331.2012.03771.x
Slavinv M, Li H, Khatri M, Frankenfeld C. Dietary magnesium and migraine in adults: a cross-sectional analysis of the National Health and Nutrition Examination Survey 2001-2004. Headache. 2021;61(2):276-286 Doi: https://doi.org/10.1111/head.14065. DOI: https://doi.org/10.1111/head.14065
Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS and Silva-Néto RP. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21(3):219-223 Doi: https://doi.org/10.1080/1028415X.2016.1266133. DOI: https://doi.org/10.1080/1028415X.2016.1266133
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Adriana de Almeida Soares, Yasmine Maria Leódido Fortes, Maria Helena da Silva Curvina, Wallyson Pablo de Oliveira Souza, Raimundo Pereira Silva-Néto (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.







