Insights on the terminology and on some pathophysiological aspects of cluster headache and related conditions
DOI:
https://doi.org/10.48208/HeadacheMed.2023.24Keywords:
Trigeminal autonomic cephalgias, Cluster headache, Headache classificationAbstract
Introduction
Cluster headache and the more recently reported “related conditions”, namely
Chronic Paroxysmal Hemicrania, Short-lasting, unilateral, Neuralgiform Headache
with Conjunctival Injection and Tearing (SUNCT) Syndrome and (possibly also)
Hemicrania Continua, are one of the fascinating groups of conditions in Neurology
whose cardinal features are the almost absolute unilaterality of pain, its excruciating
severity, besides the prominent mainly facial autonomic disturbances and overall the
intriguing biorhythmicity.Beyond any doubt, the progress of our knowledge about the
mechanisms of these conditions has been considerable, but there is always room for
reflection on where we are and where we can go.
Objective
The objectives of the present study are to analyze the metrics of publications on
the pathophysiology of these conditions, to explore in detail how proper the term
”Trigeminal Autonomic Cephalgia” is, and to comment on their numerous synonyms.
Comment
Much is needed to know the exact structures and circuitry involved in the pathophysiology of these conditions; accordingly, a non-compromising and just descriptive term
might be useful. Along this line of reasoning and bearing in mind the cardinal points
of such conditions, namely, pain in the trigeminal territory, prominent autonomic
symptoms, prominent chronobiological features, and the excruciating character of
the pain, a terminological possibility would be: Unilateral with Prominent Rhythmicity
and Autonomic Symptoms Excrutiating Cephalgia (UPRASEC).
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