Changes in cerebrospinal fluid in patients with fibromyalgia

Authors

  • Louana Cassiano da S. Lima Universidade Federal de Pernambuco
  • Marcelo Moraes Valença Universidade Federal de Pernambuco

DOI:

https://doi.org/10.48208/HeadacheMed.2015.2

Keywords:

Fibromyalgia, Cerebrospinal fluid

Abstract

Fibromyalgia is a chronic disorder with unknown etiology and pain is the main characteristic. Cerebrospinal fluid levels of neurotransmitters and neuropeptides can give information about the neuronal activity of central nervous system in patients with fibromyalgia. The objective of this research is to review the main alterations of neurotransmitters and neuropeptides in cerebrospinal fluid in patients with fibromyalgia. ScieLo, Lilacs and PubMed databases were searched, without year limitation, in Portuguese, English and Spanish idioms, using the keywords "fibromyalgia" and "cerebrospinal fluid". 120 studies were found and, after analysis, 14 were included in this research. Some substances were relates to fibromyalgia, which is in agreement with some researches that define fibromyalgia as a central nervous system disorder.

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Author Biographies

Louana Cassiano da S. Lima, Universidade Federal de Pernambuco

Doutoranda do Programa de Pós-graduação em Neuropsiquiatria e Ciências do Comportamento, Universidade Federal de Pernambuco, Recife, Brasil. Bolsista da Facepe

Marcelo Moraes Valença, Universidade Federal de Pernambuco

Coordenador do Programa de Pós-graduação em Neuropsiquiatria e Ciências do Comportamento, Universidade Federal de Pernambuco, Recife, Brasil

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Published

2015-03-31

How to Cite

1.
Lima LC da S, Valença MM. Changes in cerebrospinal fluid in patients with fibromyalgia. Headache Med [Internet]. 2015 Mar. 31 [cited 2024 Mar. 28];6(1):6-11. Available from: https://headachemedicine.com.br/index.php/hm/article/view/401

Issue

Section

Review

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