The investigation of sleep disorders in patients with cluster headache

Introduction: Recent findings regarding cluster headache (CH) have led to studies of the relationship between the hypothalamic and respiratory systems and the correlation between this relationship and sleep apnea as a comorbidity. Objectives: This study aimed to determine the prevalence of obstructive sleep apnea in a population of CH patients and to compare it with that in healthy controls. Methods: We studied 37 patients suffering from episodic cluster headache and a control group consisting of 35 individuals. Results: The incidence of obstructive sleep apnea (OSA) was higher in the CH group (58.3%) than in the control group (14.3%) and was also higher than the worldwide average (2% to 4%). Patients with CH in our study were 8.4 times more likely to exhibit OSA than were normal individuals (p lower then 0.001). This risk increased to 24.38 in patients with a BMI greater than 25 kg/m2 and to 13.5 in patients over 40 years of age. Conclusion: We suggest that polysomnography should be carried out routinely in CH patients with a BMI of more than 25 kg/m2 or who are over 40 years of age.


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