Ophthalmoplegic Migraine

Ophthalmoplegic migraine (OM) is a rare syndrome in which episodic fixed unilateral headaches are associated with ipsilateral ophthalmoplegia. Its pathophysiology remains obscure. We describe a patient with OM according to the International Headache Society (IHS-2004) criteria, who had an unusual demographic and clinic presentation. The first OM episode occurred in adult life, the side of the pain changed in one episode and she also has oculomotor abnormalities without pain. We discuss the differential diagnosis and the need for etiologic investigation in theses cases.


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