Headache Medicine 2020, 11(4):98 ISSN 2178-7468, e-ISSN 2763-6178
98
ASAA
DOI: 10.48208/HeadacheMed.2020.28
Headache Medicine
© Copyright 2020
Commentary
Rhinosinusitis as a cause of headache
Diego Belandrino Swerts
Albert Einstein Faculty of Medicine, Neurology, São Paulo, São Paulo, Brazil
The article published by Ceriani and Silberstein
1
addresses, in the format of a systematic review, the
relationship between headache and rhinosinusitis, showing that most of these cases are over diag-
nosed in patients who actually have primary headaches, the majority being migraines. In addition,
the article emphasizes the underdiagnosed sphenoid rhinosinusitis which can have great morbidity
and even mortality.
The article reviews the concepts of acute rhinosinusitis (1 day to 4 weeks), recurrent acute respiratory
syndrome (ARS) (four or more episodes lasting 7 days in one year) and chronic rhinosinusitis (persistent
beyond 12 weeks). The article then discusses the morphological, etiological, diagnostic and treatment
review of these diseases.
Acute respiratory syndromes are mostly viral, with adenovirus, inuenza and parainuenza as the most
prevalent agents. Bacterial infections have as main agents
Streptococcus pneumoniae and Haemoph-
ilus inuenza
. The clinical presentation usually leads to purulent nasal discharge, accompanied by
nasal obstruction and/or pain pressure fullness. Altered sense of smell, cough, halitosis, dental pain,
pharyngitis, and otologic symptoms may be present.
Migraine symptoms, such as nausea, photophobia, phonophobia were seen in the minority of patients
in the studies. In addition, ARS headache is bilateral, in pressure with worsening frontal compression,
less common symptoms in primary headaches. In chronic respiratory syndrome (CRS), headache and
facial pain are even less common symptoms. The studies analyzed in the systematic review show that
primary headaches should always be considered in patients with rhinosinusitis, and most patients in
the studies ended up switching the diagnosis to primary headache after revaluation.
The article continues with a review of treatment of ARS cases, showing that symptomatic patients should
be the rst option, in cases with suspected bacterial agents, amoxicillin proved to be the rst-line treat-
ment, with association with clavulanate in patients with suspected resistance to amoxicillin (smokers,
diabetics, recent use of antibiotics), the treatment of CRS was indicated with topical corticosteroids
and saline wash.
Finally, the article discusses the importance of suspecting sphenoid rhinosinusitis, which can develop with
photophobia, lacrimation, cranial nerve palsies, fever, epistasis, and visual symptoms. The importance
of investigating for this condition is due to complications such as bacterial meningitis, sinus thrombosis,
abscess, hypophysitis that are associated with high morbidity and even mortality.
Thus, in a very well-written article, the authors go through the management of the patient with a previous
diagnosis of rhinosinusitis, reporting through the symptoms, the importance of reviewing the diagnosis
and suspecting primary headaches. In addition, it eases the management of these conditions, and
emphasizes the importance of excluding the diagnosis of sphenoidal rhinosinusitis in these cases.
References
Ceriani CE, Silberstein SD. Headache and rhinosinusitis: A review.
Cephalalgia
2021;41:453 -463
diegobelandrino@gmail.com
Received: October 7, 2020
Accepted: November 14,2020