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Headache Medicine, v.3, n.1, p.45, Jan./Feb./Mar. 2012 45
Cognition in women with migraine (abstract)
Cognição em mulheres com migrânea (resumo)
Background:Background:
Background:Background:
Background: There is a consensus in clinical practice
that women in menopause transition relate cognitive complaints
mainly from memory. Some studies reported that psychological
symptoms may be associated with cognitive impairment. These
hypotheses have not been proven and controversies in the
literature are presented.This study aimed to compare the
cognitive performance and their associations with affective
variables between groups of women at three stages of
menopause with without aura migraine.
Method:Method:
Method:Method:
Method: Participants 85 women divided into five groups:
perimenopause with migraine (n = 16), perimenopausal
without migraine (n = 18), premenopausal women with migraine
(n = 20) premenopausal women without migraine (n = 15)
and late postmenopausal (n = 16, between five and ten years
after last menstruation). In a meeting were applied Depression
Inventory, Anxiety Inventory, Mini-Mental State Examination,
WAIS III (Digits reverse and direct, Search for Symbols, Codes,
Matrix Reasoning), Reproduction and Evocation Figure Rey,
Rey Word List , Semantic Fluency, Stroop test. Comparisons
were performed between groups: 1) pre-menopause and
perimenopause with and without migraine, 2) premenopausal,
perimenopausal and postmenopausal women.
Results:Results:
Results:Results:
Results: The first comparison group in premenopausal
women with migraine had a worse performance on tasks
that assessed the Stroop test words (p = 0.04), direct digit
(p = 0.02) and inverse digit (p = 0.01) , abstract visual
reasoning (p = 0.005) and anxiety (p = 0.0006) compared
with the premenopause without migraine. The perimenopausal
groups with and without migraine did not show differences
in cognition, only anxiety (p = 0.04). The perimenopausal
group without migraine got worse scores than the
premenopausal women without migraine in the tests that
assessed attention (p = 0.04), processing speed (p = 0.02),
inhibitory control (p = 0.008) and anxiety (p = 0.04). No
differences were observed between the groups premenopausal
and perimenopausal migraine with migraine. Few and weak
associations were established between the affective and
Vera Lucia Gomes Santiago
Universidade Federal de Pernambuco – UFPE. Pós-graduação de Neuropsiquiatria e Ciências do
Comportamento (área de concentração: Neuropsicopatologia). PhD Thesis. 2012
Orientador: Marcelo Moraes Valença
Santiago VL. Cognition in women with migraine (abstract). Headache Medicine. 2012;3(1):45
Correspondence
VV
VV
V
era Lera L
era Lera L
era L
ucia Gomes Santiagoucia Gomes Santiago
ucia Gomes Santiagoucia Gomes Santiago
ucia Gomes Santiago
veragsantiago@gmail.com
cognitive variables in the four groups. In the second
comparison subjects, perimenopausal and postmenopausal
women had worse scores than premenopausal tasks that
assessed processing speed (p = 0.02, p = 0.04) inhibitory
control (p = 0.02) and abstract reasoning (p = 0.02). On a
scale of severity of symptoms of anxiety groups premenopausal
and postmenopausal had lower scores than the perimenopause
(p = 0.03). Associations were evident between anxiety and
depression scores and cognitive tests in postmenopausal
group.
Conclusion:Conclusion:
Conclusion:Conclusion:
Conclusion: Premenopausal women with migraine
showed a decrease in attention, memory, abstract reasoning.
Perimenopausal and postmenopausal women showed a
decrease in speed of information processing, attention,
inhibitory control and visual abstract reasoning when compared
with premenopausal women. The presence of migraine caused
an increased intensity of anxiety symptoms. Perimenopause is
the period most susceptible to anxiety.
THESESTHESES
THESESTHESES
THESES