
Headache Medicine  
  
ISSN 2178-7468 
  
e
-ISSN 2763-6178  
 
v.11 
  
Supplement 
  
p. 72 
 
October 2020.
72
ASAA
DOI: 10.48208/HeadacheMed.2020.Supplement.72
Oliveira, A.; Mercante, J.; Peres, M.; Molina, M.; Lotufo, P.; Benseñor, Goulart, A.
Headache Medicine
Physical inactivity and headache disorders: cross-sectional analysis in the 
Brazilian longitudinal study of adult health (ELSA-Brasil)
Arao Oliveira, Juliane Mercante, Mario Peres, Maria Molina, Paulo Lotufo, Isabela Benseñor, Alessandra Goulart
Universidade de São Paulo
Background
Physical inactivity has been linked to headache disorders, but data regarding the current recommended leisure-time (LTPA) and commuting 
physical activity (CPA) levels is unknown. 
Objective
To test the associations between headache disorders (denite and probable migraine tension type headache-TTH) and physical inactivity 
in these domains (LTPA and CPA) in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). 
Methods
In a cross-sectional analysis, logistic regression models computed the odds ratio (OR) for the relationship between headache disorders 
and physical activity (LTPA and CPA) in the following levels: “active” (Reference),  “insuciently active”, and “inactive”. The full models were 
controlled for the effects  of sociodemographic data, cardiovascular risk prole, and use of headache medication (migraine prophylaxis) 
Results
Of 15,0105 participants, 14,847 (45.6 % of men and 54.4 % women) responded the baseline interviews regarding physical activity 
levels and headache disorders. Overall, most signicant physical inactivity was observed in LTPA domain for denite migraine [OR: 
1.32 (1.10-1.57)] and probable migraine [OR: 1.33 (1.17-1.50)]. Similar ndings were replicated by sex. Physical inactivity (LTPA) was 
positively associated with denite migraine in women [OR: 1.29 (1.04-1.59)], probable migraine in both men [OR: 1.40 (1.15-1.69)] 
and women [OR: 1.29 (1.04-1.59)]. Physical inactivity in CPA domain was associated to increased OR for probable TTH in men [OR: 
1.33 (1.01-1.75)], while CPA was inversely associated to denite migraine [OR: 0.79 (0.64-0.98)] and probable migraine [OR: 0.80 
(0.67-0.96)] in women. Considering all headaches, unmet vigorous physical activity levels were associated to increased OR for denite 
migraine [OR: 1.36 (1.13-1.65)] and probable migraine [OR: 1.37 (1.20-1.57)]. Finally,  we found higher odds  for  daily headaches 
among LTPA-inactive [OR: 1.73 (1.20-2.49)] and CPA-insufciently active [ OR: 1.36 (1.04-1.79)] participants.
Conclusion
Physical inactivity is associated with headache disorders in the ELSA-Brasil study, with distinct associations regarding headache subtype, 
sex, physical activity domain and intensity, and headache frequency.